GATA2 deficiency exacerbates chronic liver injury via disrupting hepatocyte death-regeneration balance: Clinical, histopathological, and molecular evidence

doi:10.4252/wjsc.v18.i2.112940

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World Journal of Stem Cells

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1948-0210

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World J Stem Cells. Feb 26, 2026; 18(2): 112940
Published online Feb 26, 2026. doi: 10.4252/wjsc.v18.i2.112940

Table 4 Dynamic changes in the patient’s liver biochemical indexes

Date	ALT (U/L)	AST (U/L)	TBil (μmol/L)	DBil (μmol/L)	ALP (U/L)	GGT (U/L)	ALB (g/L)	GLB (g/L)
Date	Reference: 7-40	Reference: 13-35	Reference: 5-21	Reference: 0-3.4	Reference: 50-135	Reference: 7-45	Reference: 40-55	Reference: 20-40
December 3, 2021	73↑	53↑	115.1↑	56.4↑	166↑	153↑	28↓	26
December 5, 2021	51↑	43↑	106.4↑	49↑	158↑	129↑	27.6↓	27
December 9, 2021	26	34	83.2↑	38.8↑	149↑	118↑	27.7↓	26
December 12, 2021	21	32	76.9↑	35.1↑	131	105↑	30.9↓	24
December 14, 2021	15	27	84.4↑	39.7↑	142↑	97↑	28.7↓	27
December 17, 2021	13	26	73.3↑	31↑	150↑	85↑	33.8↓	25
August 4, 2022	21	26	15.4	4.5↑	176↑	62↑	37.4↓	25
August 6, 2022	44↑	15	20.9↑	5.5↑	157↑	48↑	32.5↓	19↓
August 8, 2022	76↑	26	20.3	6.2↑	153↑	45	32.7↓	19↓

“↑” indicates values above the normal range, and “↓” denotes values below the normal range. ALT: Alanine transaminase; AST: Aspartate aminotransferase; TBil: Total bilirubin; DBil: Direct bilirubin; ALP: Alkaline phosphatase; GGT: Gamma-glutamyl transferase; ALB: Albumin; GLB: Globulin.

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Citation: Chen YF, Li SQ, Zhang J, Ma WT, Zhou Y, Rao JX, Yi Y, Cheng QJ, Zhong WW, Chen H, Chen YH, Luo YW, He YH. GATA2 deficiency exacerbates chronic liver injury via disrupting hepatocyte death-regeneration balance: Clinical, histopathological, and molecular evidence. World J Stem Cells 2026; 18(2): 112940
URL: https://www.wjgnet.com/1948-0210/full/v18/i2/112940.htm
DOI: https://dx.doi.org/10.4252/wjsc.v18.i2.112940

Chen YF, Li SQ, Zhang J, Ma WT, Zhou Y, Rao JX, Yi Y, Cheng QJ, Zhong WW, Chen H, Chen YH, Luo YW, He YH. GATA2 deficiency exacerbates chronic liver injury via disrupting hepatocyte death-regeneration balance: Clinical, histopathological, and molecular evidence. World J Stem Cells 2026; 18(2): 112940 [PMID: 41808888 DOI: 10.4252/wjsc.v18.i2.112940]

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