GATA2 deficiency exacerbates chronic liver injury via disrupting hepatocyte death-regeneration balance: Clinical, histopathological, and molecular evidence

doi:10.4252/wjsc.v18.i2.112940

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.

World J Stem Cells. Feb 26, 2026; 18(2): 112940
Published online Feb 26, 2026. doi: 10.4252/wjsc.v18.i2.112940

Table 3 Primary antibodies used in this study

Antibody	Source	Lot number	Manufacturer	Molecular weight (kDa)
Cleaved caspase-3	Rabbit mAb	9664	Cell Signaling Technology, Danvers, MA, United States	17
GAPDH	Mouse mAb	MAB45855	Bioswamp, Wuhan, China	36
GATA2	Mouse mAb	sc-267	Santa Cruz, TX, United States	50
GRP78	Rabbit mAb	ab108615	Abcam, Cambridge, MA, United States	78
GPX4	Mouse mAb	sc-166437	Santa Cruz, TX, United States	21
UCP2	Mouse mAb	sc-390189	Santa Cruz, TX, United States	70
HSP60	Mouse mAb	sc-376240	Santa Cruz, TX, United States	60
PCNA	Mouse mAb	sc-25280	Santa Cruz, TX, United States	36
MCAD	Mouse mAb	sc-365109	Santa Cruz, TX, United States	45
MLKL	Rabbit pAb	PA5-34733	Thermo Fisher Scientific, Waltham, MA, United States	54
PPARα	Mouse mAb	MA5-37652	Thermo Fisher Scientific, Waltham, MA, United States	55
p-MLKL	Rabbit mAb	37333S	Cell Signaling Technology, Danvers, MA, United States	54

GATA2: GATA binding protein 2; GRP78: Glucose-regulated protein 78; GPX4: Glutathione peroxidase 4; UCP2: Uncoupling protein 2; HSP60: Heat shock protein 60; PCNA: Proliferating cell nuclear antigen; MCAD: Medium chain acyl-CoA dehydrogenase; MLKL: Mixed lineage kinase domain-like protein; PPARα: Peroxisome proliferator-activated receptor alpha; p-MLKL: Phosphorylated mixed lineage kinase domain-like protein; mAb: Monoclonal antibody; pAb: Polyclonal antibody.

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Citation: Chen YF, Li SQ, Zhang J, Ma WT, Zhou Y, Rao JX, Yi Y, Cheng QJ, Zhong WW, Chen H, Chen YH, Luo YW, He YH. GATA2 deficiency exacerbates chronic liver injury via disrupting hepatocyte death-regeneration balance: Clinical, histopathological, and molecular evidence. World J Stem Cells 2026; 18(2): 112940
URL: https://www.wjgnet.com/1948-0210/full/v18/i2/112940.htm
DOI: https://dx.doi.org/10.4252/wjsc.v18.i2.112940

Chen YF, Li SQ, Zhang J, Ma WT, Zhou Y, Rao JX, Yi Y, Cheng QJ, Zhong WW, Chen H, Chen YH, Luo YW, He YH. GATA2 deficiency exacerbates chronic liver injury via disrupting hepatocyte death-regeneration balance: Clinical, histopathological, and molecular evidence. World J Stem Cells 2026; 18(2): 112940 [PMID: 41808888 DOI: 10.4252/wjsc.v18.i2.112940]

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