Human bone marrow-derived mesenchymal stem cells alleviate fluoxetine-resistant depression-like behaviors in mice by multi-target effects in the hippocampus

Figure 6 Human bone marrow-derived mesenchymal stem cells improved hippocampal function in stressed mice. A: Western blot plot of protein in the different groups; B-F: Relative expression levels of glial fibrillary acidic protein (B), S100-β (C), NeuN (D), MAP2 (E), and DCX (F) normalized to GAPDH. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001. Data were analyzed using one-way analysis of variance followed by Tukey’s multiple-comparisons test (mean ± SEM, n = 4 per group). GFAP: Glial fibrillary acidic protein; FLX: Fluoxetine; hBMSCs: Human bone-marrow-derived mesenchymal stem cells.