Human umbilical cord mesenchymal stem cells repair islet structure and function in diabetic rats through metabolic reprogramming

Table 3 Results of correlation analysis between key differential metabolites and biochemical indicators in the diabetes mellitus group vs control group

Biochemical index	Differential metabolite ID	Correlation coefficient	P value
C-peptide	MW0015937	0.788548168	< 0.001
C-peptide	MW0128176	0.876654109	< 0.001
C-peptide	MW0053755	0.689428985	< 0.01
C-peptide	MW0106148	0.766521683	< 0.01
C-peptide	MW0141637	0.766521683	< 0.01
C-peptide	MEDTN02450	0.674010446	< 0.01
C-peptide	MW0123548	-0.621146881	< 0.05
C-peptide	MW0014969	0.570485965	< 0.05
C-peptide	MW0006200	0.546256832	< 0.05
C-peptide	MW0123754	0.557270074	< 0.05
C-peptide	MW0054549	0.605728342	< 0.05
C-peptide	MW0148399	0.546256832	< 0.05
C-peptide	MW0113931	0.610133639	< 0.05
C-peptide	FDATN00900	-0.640970718	< 0.05
C-peptide	ZINC1629864	-0.557270074	< 0.05
C-peptide	MW0055257	0.539648886	< 0.05
FINS	MW0106148	0.815384615	< 0.001
FINS	MW0006200	0.824175824	< 0.001
FINS	MW0054549	0.920879121	< 0.001
FINS	MW0053755	0.736263736	< 0.01
FINS	MW0123548	-0.736263736	< 0.01
FINS	MW0015937	0.679120879	< 0.01
FINS	MW0014969	0.78021978	< 0.01
FINS	MW0055456	0.696703297	< 0.01
FINS	MW0141637	0.753846154	< 0.01
FINS	MEDP1339	0.608791209	< 0.05
FINS	MW0157815	0.661538462	< 0.05
FINS	MW0154243	0.635164835	< 0.05
FINS	MW0012191	0.657142857	< 0.05
FINS	MEDN0785	0.643956044	< 0.05
FINS	MW0123754	0.657142857	< 0.05
FINS	MW0128176	0.652747253	< 0.05
FINS	FDATN00900	-0.595604396	< 0.05
FINS	ZINC1629864	-0.538461538	< 0.05
FBG	MW0053755	-0.879828407	< 0.001
FBG	FDATN00900	0.793830142	< 0.001
FBG	MW0106148	-0.749728467	< 0.01
FBG	MW0014969	-0.670345453	< 0.01
FBG	MW0006200	-0.685781039	< 0.01
FBG	MW0123754	-0.705626793	< 0.01
FBG	MW0141637	-0.756343718	< 0.01
FBG	MW0054549	-0.725472546	< 0.01
FBG	MW0148399	-0.72767763	< 0.01
FBG	MW0128176	-0.776189472	< 0.01
FBG	MW0113931	-0.679165788	< 0.01
FBG	MW0157815	-0.641679365	< 0.05
FBG	MW0123548	0.606398025	< 0.05
FBG	MW0154243	-0.557886183	< 0.05
FBG	MW0012191	-0.551270932	< 0.05
FBG	MW0015937	-0.624038695	< 0.05
FBG	MEDN0785	-0.546860764	< 0.05
FBG	MW0055456	-0.544655681	< 0.05
FBG	MEDTN02450	-0.599782774	< 0.05
FBG	MW0152407	-0.538040429	< 0.05
FBG	ZINC1629864	0.56229635	< 0.05
FBG	MW0055257	-0.617423444	< 0.05
HOMA-IR	MW0053755	-0.872248812	< 0.001
HOMA-IR	MW0106148	-0.775332277	< 0.01
HOMA-IR	MW0014969	-0.676213094	< 0.01
HOMA-IR	MW0123754	-0.735684604	< 0.01
HOMA-IR	MW0141637	-0.696036931	< 0.01
HOMA-IR	MW0148399	-0.707050173	< 0.01
HOMA-IR	MW0128176	-0.777534926	< 0.01
HOMA-IR	FDATN00900	0.773129629	< 0.01
HOMA-IR	MW0123548	0.535243589	< 0.05
HOMA-IR	MW0154243	-0.660794555	< 0.05
HOMA-IR	MW0114597	0.570485965	< 0.05
HOMA-IR	MW0015937	-0.618944233	< 0.05
HOMA-IR	MW0144473	-0.610133639	< 0.05
HOMA-IR	MW0006200	-0.550662129	< 0.05
HOMA-IR	MW0054549	-0.570485965	< 0.05
HOMA-IR	MW0113931	-0.632160124	< 0.05
HOMA-IR	MW0152407	-0.568283317	< 0.05
HOMA-IR	MW0055257	-0.625552178	< 0.05
GHb	MW0141637	-0.815384615	< 0.001
GHb	MW0054549	-0.806593407	< 0.001
GHb	MW0053755	-0.683516484	< 0.01
GHb	MW0123548	0.793406593	< 0.01
GHb	MW0106148	-0.793406593	< 0.01
GHb	MW0015937	-0.679120879	< 0.01
GHb	MW0014969	-0.775824176	< 0.01
GHb	MW0006200	-0.797802198	< 0.01
GHb	MW0123754	-0.740659341	< 0.01
GHb	MW0128176	-0.758241758	< 0.01
GHb	FDATN00900	0.714285714	< 0.01
GHb	MEDP1339	-0.551648352	< 0.05
GHb	MW0157815	-0.538461538	< 0.05
GHb	MW0154243	-0.665934066	< 0.05
GHb	MW0114597	0.657142857	< 0.05
GHb	MW0012191	-0.604395604	< 0.05
GHb	MEDN0785	-0.648351648	< 0.05
GHb	MW0144473	-0.591208791	< 0.05
GHb	MW0055456	-0.661538462	< 0.05
GHb	MEDTN02450	-0.621978022	< 0.05
GHb	MW0113931	-0.648351648	< 0.05
GHb	MW0055257	-0.657142857	< 0.05
GSP	MW0053755	-0.705494505	< 0.01
GSP	MW0123548	0.714285714	< 0.01
GSP	MW0012191	-0.687912088	< 0.01
GSP	MW0106148	-0.692307692	< 0.01
GSP	MW0015937	-0.789010989	< 0.01
GSP	MW0014969	-0.701098901	< 0.01
GSP	MEDN0785	-0.714285714	< 0.01
GSP	MW0006200	-0.723076923	< 0.01
GSP	MW0055456	-0.723076923	< 0.01
GSP	MW0141637	-0.731868132	< 0.01
GSP	MW0054549	-0.753846154	< 0.01
GSP	MEDTN02450	-0.692307692	< 0.01
GSP	MW0128176	-0.723076923	< 0.01
GSP	MW0152407	-0.701098901	< 0.01
GSP	MEDP1339	-0.556043956	< 0.05
GSP	MW0154243	-0.595604396	< 0.05
GSP	MW0114597	0.556043956	< 0.05
GSP	MW0144473	-0.547252747	< 0.05
GSP	MW0123754	-0.542857143	< 0.05
GSP	FDATN00900	0.591208791	< 0.05
GSP	ZINC1629864	0.569230769	< 0.05

FINS: Fasting insulin; FBG: Fasting blood glucose; HOMA-IR: Homeostasis model assessment of insulin resistance; GHb: Glycosylated hemoglobin; GSP: Glycosylated serum protein.