Therapeutic potential of umbilical cord-derived mesenchymal stem cells in ameliorating ovarian aging: Insights from single-cell analysis

doi:10.4252/wjsc.119325

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Stem Cells. Oct 26, 2026; 18(10): 119325
Published online Oct 26, 2026. doi: 10.4252/wjsc.119325

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Figure 10 External validation of ovarian aging-associated transcriptional alterations using GSE232309. A: UMAP of granulosa cells from young and aged mice showing substantial overlap between age groups; B: Klotho expression in young and aged granulosa cells; C: Oxidative phosphorylation-related gene signature score calculated from representative oxidative phosphorylation genes. OXPHOS: Oxidative phosphorylation.

Citation: Zhang JN, Tian S, Guo XM, Zhang Q, Shang J, Yao YQ. Therapeutic potential of umbilical cord-derived mesenchymal stem cells in ameliorating ovarian aging: Insights from single-cell analysis. World J Stem Cells 2026; 18(10): 119325
URL: https://www.wjgnet.com/1948-0210/full/v18/i10/119325.htm
DOI: https://dx.doi.org/10.4252/wjsc.119325

Zhang JN, Tian S, Guo XM, Zhang Q, Shang J, Yao YQ. Therapeutic potential of umbilical cord-derived mesenchymal stem cells in ameliorating ovarian aging: Insights from single-cell analysis. World J Stem Cells 2026; 18(10): 119325 [DOI: 10.4252/wjsc.119325]

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