©The Author(s) 2026.
World J Stem Cells. Jan 26, 2026; 18(1): 114119
Published online Jan 26, 2026. doi: 10.4252/wjsc.v18.i1.114119
Published online Jan 26, 2026. doi: 10.4252/wjsc.v18.i1.114119
Table 2 Characteristics of mesenchymal stem cells supporting their use for age-related disorders
| Feature | Benefit for age-related disorders |
| Multilineage differentiation | Regenerates multiple tissue types damaged by aging |
| Low immunogenicity | Reduces risk of immune rejection |
| Immunomodulation | Controls chronic inflammation common in aging |
| Ease of isolation and expansion | Facilitates clinical application |
| Exosome secretion | Delivers anti-inflammatory, antioxidant and regenerative factors |
| Combats oxidative stress | Protects cells from age-related damage |
| Rejuvenation potential | Restores function of aged stem cells |
- Citation: Choudhery MS, Arif T, Mahmood R. Aging puzzle: A closer look on the complex dilemma of autologous stem cell therapy. World J Stem Cells 2026; 18(1): 114119
- URL: https://www.wjgnet.com/1948-0210/full/v18/i1/114119.htm
- DOI: https://dx.doi.org/10.4252/wjsc.v18.i1.114119