Breast cancer stem cell activity driven by ME18D gene expression in the tumor microenvironment

Figure 6 Single-cell spatial transcriptomic analysis of breast cancer tissues. A: Tissue morphology of three breast cancer samples showing typical tumor architecture with cancer cell aggregation and stromal distribution; B: Spatial distribution of risk scores based on stem cell-related genes, with high-risk regions (red/orange) and low-risk regions (green/blue) displaying distinct clustering patterns; C: Cell type annotation identifying major cellular components including cancer cells, immune cells, fibroblasts, and endothelial cells with specific spatial distribution patterns throughout the tumor microenvironment.