Adipose-derived mesenchymal stem cells from solid tissue and lipoaspirates: A comparative study of phenotype, growth, and secretome

Figure 3 Similar capacity of colony-forming and multilineage differentiation of primary adipose-derived mesenchymal stem cells. A: Ability to form colony units by human primary adipose-derived mesenchymal stem cells; B: Capacity of multi-lineage differentiation of adipocytes, osteocytes, and chondrocytes by human primary adipose-derived mesenchymal stem cells; C: Expression of differentiated marker genes before and after differentiation induction, where alkaline phosphatase (ALP), parathyroid hormone-related protein (PTHR), and collagen type I alpha 1 chain (COL1A1) are markers for osteogenesis; SRY-box 9 (SOX9) and COL3A1 are markers for chondrogenesis; and LEPTIN and peroxisome proliferator–activated receptor (PPAR) are markers for adipogenesis. ^aP < 0.05. AD: Adipose tissue; CFU: Colony-forming unit.