Exploring the critical therapeutic window: Dose-frequency optimization of human umbilical cord mesenchymal stem cells for preclinical asthma treatment

Figure 6 Effects of human umbilical cord blood-derived mesenchymal stem cells on the lung function of acute ovalbumin-induced asthmatic mice. A: Forced expiratory volume 0.1/forced vital capacity; B: Dynamic lung compliance; C: Airway resistance; D: Respiratory system elastic resistance; E: Forced vital capacity. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001, ^dP < 0.0001. Bonferroni correction was applied to evaluate lung function metrics in multiple treatment groups. FEV: Forced expiratory volume; FVC: Forced vital capacity; Cdyn: Dynamic lung compliance; RL: Airway resistance; Re: Respiratory system elastic resistance.