Exploring the critical therapeutic window: Dose-frequency optimization of human umbilical cord mesenchymal stem cells for preclinical asthma treatment

doi:10.4252/wjsc.v17.i9.109715

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Sep 26, 2025; 17(9): 109715
Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.109715

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Figure 3 Gross lung photography of ovalbumin-induced asthmatic mice treated with different dosages of human umbilical cord blood-derived mesenchymal stem cell. A-E: Gross lung images of a group of control, model, and three different dosages of human umbilical cord blood-derived mesenchymal stem cells treatment. L-D HUC-MSC: Low dosage (1 × 10⁵) of human umbilical cord blood-derived mesenchymal stem cell; M-D HUC-MSC: Medium dosage (2 × 10⁵) of human umbilical cord blood-derived mesenchymal stem cell; H-D HUC-MSC: High dosage (4 × 10⁵) of human umbilical cord blood-derived mesenchymal stem cell.

Citation: Chen QH, Zheng JY, Zhu YQ, Zhang JY, Lin CY, Zhuang XE, Cheng J, Huang XY. Exploring the critical therapeutic window: Dose-frequency optimization of human umbilical cord mesenchymal stem cells for preclinical asthma treatment. World J Stem Cells 2025; 17(9): 109715
URL: https://www.wjgnet.com/1948-0210/full/v17/i9/109715.htm
DOI: https://dx.doi.org/10.4252/wjsc.v17.i9.109715

Chen QH, Zheng JY, Zhu YQ, Zhang JY, Lin CY, Zhuang XE, Cheng J, Huang XY. Exploring the critical therapeutic window: Dose-frequency optimization of human umbilical cord mesenchymal stem cells for preclinical asthma treatment. World J Stem Cells 2025; 17(9): 109715 [PMID: 41025110 DOI: 10.4252/wjsc.v17.i9.109715]

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