Exercise combined with induced pluripotent stem cells enhances the Wnt1-Lmx1a loop in the midbrain of Parkinsonian mice to alleviate Parkinsonian symptoms

doi:10.4252/wjsc.v17.i9.109330

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Sep 26, 2025; 17(9): 109330
Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.109330

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Figure 3 Immunofluorescence localization images of brain tissues from mice in sedentary Parkinson’s disease group, induced pluripotent stem cell-treated Parkinson’s disease group, and exercise and induced pluripotent stem cell-treated Parkinson’s disease group. A: Results of immunofluorescence staining of mouse brain tissue sections, blue: DAPI, green: OCT4; B: Relative expression of OCT4 in mouse brain tissue sections. ^cP < 0.05; ^dP < 0.01. St: Sedentary Parkinson’s disease group; T: Induced pluripotent stem cell-treated Parkinson’s disease group; ET: Exercise and induced pluripotent stem cell-treated Parkinson’s disease group.

Citation: Jiang X, Lu ZM, Wang QL, Luo Y, Zhang J. Exercise combined with induced pluripotent stem cells enhances the Wnt1-Lmx1a loop in the midbrain of Parkinsonian mice to alleviate Parkinsonian symptoms. World J Stem Cells 2025; 17(9): 109330
URL: https://www.wjgnet.com/1948-0210/full/v17/i9/109330.htm
DOI: https://dx.doi.org/10.4252/wjsc.v17.i9.109330

Jiang X, Lu ZM, Wang QL, Luo Y, Zhang J. Exercise combined with induced pluripotent stem cells enhances the Wnt1-Lmx1a loop in the midbrain of Parkinsonian mice to alleviate Parkinsonian symptoms. World J Stem Cells 2025; 17(9): 109330 [PMID: 41025098 DOI: 10.4252/wjsc.v17.i9.109330]

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