Exercise combined with induced pluripotent stem cells enhances the Wnt1-Lmx1a loop in the midbrain of Parkinsonian mice to alleviate Parkinsonian symptoms

Figure 2 The results of rotarod test and open field test, as well as changes in serum epinephrine and nerve growth factor protein expression levels in mice of each group. A: The changes in the rotarod test performance of mice in each group; B: The changes in the open field test of sedentary and exercise Parkinson’s disease group; C: The enzyme-linked immunosorbent assay analysis of epinephrine in the serum of mice in each group; D: The enzyme-linked immunosorbent assay analysis of nerve growth factor in the serum of mice in each group. ^dP < 0.01. St: Sedentary Parkinson’s disease group; E: Exercise Parkinson’s disease group; T: Induced pluripotent stem cell-treated Parkinson’s disease group; ET: Exercise and induced pluripotent stem cell-treated Parkinson’s disease group; NGF: Nerve growth factor.