Exercise combined with induced pluripotent stem cells enhances the Wnt1-Lmx1a loop in the midbrain of Parkinsonian mice to alleviate Parkinsonian symptoms

doi:10.4252/wjsc.v17.i9.109330

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Sep 26, 2025; 17(9): 109330
Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.109330

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Figure 1 Validation of Parkinson’s disease mouse model by rotarod test, open field test, and tyrosine hydroxylase immunohistochemistry. A: Rotarod latency in control group and Parkinson’s disease (PD) model group; B: Open-field test in control group and PD model group; C: Representative TH+ fiber staining in striatum (scale bars: 20 μm and 10 μm). ^cP < 0.01. Ctrl: Control group; PD: Parkinson’s disease group.

Citation: Jiang X, Lu ZM, Wang QL, Luo Y, Zhang J. Exercise combined with induced pluripotent stem cells enhances the Wnt1-Lmx1a loop in the midbrain of Parkinsonian mice to alleviate Parkinsonian symptoms. World J Stem Cells 2025; 17(9): 109330
URL: https://www.wjgnet.com/1948-0210/full/v17/i9/109330.htm
DOI: https://dx.doi.org/10.4252/wjsc.v17.i9.109330

Jiang X, Lu ZM, Wang QL, Luo Y, Zhang J. Exercise combined with induced pluripotent stem cells enhances the Wnt1-Lmx1a loop in the midbrain of Parkinsonian mice to alleviate Parkinsonian symptoms. World J Stem Cells 2025; 17(9): 109330 [PMID: 41025098 DOI: 10.4252/wjsc.v17.i9.109330]

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