Efficacy and safety of umbilical cord-derived mesenchymal stem cell-conditioned media for preventing and treating skin aging

Figure 2 Enhanced proliferation ability of skin fibroblasts by umbilical cord-derived mesenchymal stem cell-conditioned medium. A: Fibroblasts cultured for 72 hours in fibroblast medium containing 10% adipose-derived mesenchymal stem cell (ADMSC-CM) or umbilical cord-derived mesenchymal stem cell-conditioned medium (UCMSC-CM). Scale bar = 250 μm; B: Doubling time, calculated from cell growth curves, of fibroblasts cultured in fibroblast medium with 10% ADMSC-CM or UCMSC-CM; C: WST analysis results of fibroblast culture in fibroblast media with 10% ADMSC-CM or UCMSC-CM. ADMSC-CM: Adipose-derived mesenchymal stem cell-conditioned medium; UCMSC-CM: Umbilical cord-derived mesenchymal stem cell-conditioned medium.