Wumei Pills enhance intestinal stem cell - mediated repair in chemotherapy-induced mucositis via Lactobacillus reuteri - dependent modulation of the gut microbiota

Figure 6 Wumei Pills and Lactobacillus reuteri increase intestinal stem cell activity and activates the Wingless-type/β-catenin signaling pathway in chemotherapy-induced intestinal mucositis mice. A: The gene expression of Wingless-type 3, β-catenin analyzed by immunohistochemistry staining; B: Images showing immunohistochemistry staining with leucine-rich-repeat-containing G-protein-coupled receptor 5 antibodies in the jejunum. 5-FU: 5-fluorouracil; ABX: Antibiotic mixture; L. reuteri: Lactobacillus reuteri; WMP: Wumei Pills; Wnt3: Wingless-type 3; Lgr5: Leucine-rich-repeat-containing G-protein-coupled receptor 5.