Wumei Pills enhance intestinal stem cell - mediated repair in chemotherapy-induced mucositis via Lactobacillus reuteri - dependent modulation of the gut microbiota

Figure 2 Effects of Wumei Pills and Lactobacillus reuteri on general condition, intestinal inflammation, villus height and crypt depth in 5-fluorouracil and pseudo-germ-free mice. A: Body weight; B: Food intake; C and D: Diarrhea scores; E: Crypt depth; F: Villus height; G: Representative hematoxylin and eosin-stained images in the colon and jejunum. Values represent the mean ± SEM. ^aP < 0.05 vs control group; ^bP < 0.01 vs control group; ^cP < 0.001 vs control group; ^dP < 0.0001 vs 5-fluorouracil + antibiotic mixture group; ^eP < 0.05 vs 5-fluorouracil group. 5-FU: 5-fluorouracil; ABX: Antibiotic mixture; WMP: Wumei Pills; L. reuteri: Lactobacillus reuteri.