X inactive-specific transcript regulates mitochondrial function and neuronal differentiation of stem cells via IGF2BP2/CPT1A axis in models of spinal cord injury

Figure 7 X inactive-specific transcript reverses the effects of spinal cord injury on microtubule-associated protein 2 and glial fibrillary acidic protein expression. A: Real-time quantitative PCR analysis of microtubule-associated protein 2 expression, showing a significant reduction in the spinal cord injury group and reversal by X inactive-specific transcript treatment; B: Real-time quantitative PCR analysis of glial fibrillary acidic protein expression, showing a significant increase in the spinal cord injury group and reversal by X inactive-specific transcript treatment. Data are presented as mean ± SD. ^aP < 0.05 indicates sham vs spinal cord injury, ^bP < 0.05 indicates spinal cord injury vs X inactive-specific transcript, ^cP < 0.05 indicates negative control vs X inactive-specific transcript. XIST: X inactive-specific transcript; NC: Negative control; SCI: Spinal cord injury; MAP2: Microtubule-associated protein 2; GFAP: Glial fibrillary acidic protein.