Human umbilical cord mesenchymal stem cells reduce platelet α-granule release in rats via the AKT/MEK/ERK pathway during acute exposure to high-altitude hypoxia

Figure 5 Human umbilical cord mesenchymal stem cells reduce the release of platelet α-granules in rats exposed to acute high-altitude hypoxia via the protein kinase B/mitogen-activated protein kinase/extracellular-signal regulated kinase pathway. A: Expression of p-protein kinase B in the different groups; B: Expression of p-mitogen-activated protein kinase in the different groups; C: Expression of p-extracellular-signal regulated kinase in the different groups. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001. AKT: Protein kinase B; MEK: Mitogen-activated protein kinase; ERK: Extracellular-signal regulated kinase; hUC-MSC: Human umbilical cord mesenchymal stem cell.