Living bio-drug therapies using mesenchymal stem cells and exosomes for mechanically ventilated patients with acute respiratory distress syndrome: A systematic review and meta-analysis

Figure 4 Forest plot showing length of hospital stay, length of intensive care unit stay, and 6-minute walk distance test to determine the change in patients treated with mesenchymal stem cells vs the control. A: Forest plot showing length of hospital stay to determine the change in patients treated with mesenchymal stem cells (MSCs) vs the control; B: Forest plot showing length of intensive care unit stay to determine the change in patients treated with MSCs vs the control; C: Forest plot showing 6-minute walk distance test to determine the change in patients treated with MSCs vs the control. The pooled weighted mean difference, along with its 95% confidence interval, is presented. Each square represents the effect estimate of an individual study, with the size proportional to its weight in the meta-analysis; horizontal lines denote the 95% confidence interval. The diamond indicates the overall pooled effect. MSC: Mesenchymal stem cell; CI: Confidence interval.