Synovial mesenchymal stem cell-derived exosomes delivering GRPEL1 activate PINK1-mediated mitophagy to promote cartilage repair in arthritis

Figure 1 Identification of differentially expressed genes in osteoarthritis cartilage tissue. A: Volcano plot illustrating differentially expressed genes (DEGs) from the GSE169077 dataset, highlighting the significance and fold change of gene expression; B: Volcano plot depicting DEGs from the GSE114007 dataset, providing a visual summary of the statistical significance and magnitude of changes in gene expression; C: Venn diagram showing the intersection of DEGs identified in both the GSE169077 and GSE114007 datasets, indicating the common genes that are differentially expressed across the two studies. FC: Fold change.