Quercetin ameliorates oxidative stress-induced senescence in rat nucleus pulposus-derived mesenchymal stem cells via the miR-34a-5p/SIRT1 axis

Figure 6 Quercetin downregulates the expression of senescence associated secreted phenotype: IL-1β, IL-6 and MMP13. A and B: Immunofluorescence staining and quantitative analysis of IL-1β; C and D: Immunofluorescence staining and quantitative analysis of IL-6; E and F: Immunofluorescence staining and quantitative analysis of MMP-13; G-J: The protein expressions and quantitative analysis of IL-1β, IL-6 and MMP-13 in different groups. Scale bar = 100 μm. Data are represented as mean ± SD. Significant differences between groups are indicated as ^aP < 0.05, n = 3. TBHP: Tert-butyl hydroperoxide; Que: Quercetin.