Bone marrow mesenchymal stem cell-derived exosomal microRNAs target PI3K/Akt signaling pathway to promote the activation of fibroblasts

Figure 8 Inhibition of phosphatase and tensin homolog promoted cell proliferation, migration, and collagen synthesis. A: The protein levels of p-Akt and Akt in NIH3T3 cells were determined by western blot; B: Bromodeoxyuridine assay was performed to measure the proliferation ability; C: Wound healing assay was performed to measure the migratory capability; D: Collagen contraction assay was performed to evaluate the cell contractility. n = 3 per groups. Data are shown as mean ± SD. ^aP < 0.05, ^bP < 0.01.