Long noncoding RNAs in mesenchymal stromal/stem cells osteogenic differentiation: Implications in osteoarthritis pathogenesis

Table 1 Supplementary information to Figure 1 detailing source and mechanism of activity associated with modified long noncoding RNAs

Upregulated			Downregulated
lncRNAs	Function	Ref.	lncRNAs	Function	Ref.
DANCR	Increased proliferation and chondrogenesis	Wang et al[12], 2020	XIST	Increased inflammation and apoptotic rate	Lian et al[13], 2020
MALAT1	Decreased rate of synovial fibroblast proliferation	Nanus et al[14], 2020	NR024118	Inflammation, apoptosis, and ROS elevation	Mei et al[15], 2019
THRIL	Upregulated inflammatory injury and apoptosis	Liu et al[16], 2019	HULC	Increased inflammation	Chu et al[17], 2019
LINC0051	Results in anti-proliferative actions	Zhang et al[18], 2020	lncRNA-ATB	Increased inflammation	Ying et al[19], 2019
			OIP5-AS1	Decreased cell proliferation and migration, decreased cell anti-inflammatory mediator secretion	Zhi et al[20], 2020

lncRNAs: Long noncoding RNAs.