Copyright
©The Author(s) 2020.
World J Stem Cells. Feb 26, 2020; 12(2): 100-109
Published online Feb 26, 2020. doi: 10.4252/wjsc.v12.i2.100
Published online Feb 26, 2020. doi: 10.4252/wjsc.v12.i2.100
Table 2 Exosomes derived from adipose mesenchymal stem cells
| Condition | In vitro study | In vivo study (animal model / clinical use) | Results | Ref. |
| Atopic dermatitis | - | Atopic dermatitis model (Mouse) | Reduces clinical symptoms | Cho et al[35], 2018 |
| Acute cutaneous wound healing | - | Acute cutaneous wound healing (Nude mice) | Promotes fibroblast activities, re-epithelialization, vascularization in wound healing | Liu et al[36], 2019 |
| Wound healing | + | Mouse full-thickness incision wound model | Accelerates wound healing by optimizing fibroblast function | Zhang et al[37], 2018 |
| Corneal stromal cells | + | - | Role of ASC-Ex in corneal stromal cell and extra cellular matrix remodeling | Shen et al[38], 2018 |
| Apoptosis in cardiomyocyte caused by oxidative stress | + | - | Prevents apoptosis | Liu et al[39], 2019 |
| Ovarian cancer | + | - | Ovarian cancer cells inhibited by exosomes | Reza et al[40], 2016 |
| Neural injury | + | - | Could inhibit the activation of microglia cells and prevent neuroinflammation | Feng et al[41], 2019 |
- Citation: Álvarez-Viejo M. Mesenchymal stem cells from different sources and their derived exosomes: A pre-clinical perspective. World J Stem Cells 2020; 12(2): 100-109
- URL: https://www.wjgnet.com/1948-0210/full/v12/i2/100.htm
- DOI: https://dx.doi.org/10.4252/wjsc.v12.i2.100