Effects of normobaric cyclic hypoxia exposure on mesenchymal stem-cell differentiation–pilot study on bone parameters in elderly

Figure 7 Expressions of low-density lipoprotein receptor related protein 5, low-density lipoprotein receptor related protein 6 and Dickkopf Wnt signaling pathway inhibitor 1 genes. They were quantified at days 7 and 13, in mesenchymal stem cells differentiating into (A) osteoblasts or (B) adipocytes, exposed to normoxia or different cyclic hypoxia conditions. ^aP < 0.05 vs normoxia (0 h of hypoxia). DKK1: Dickkopf Wnt signaling pathway inhibitor 1; LRP6: Low-density lipoprotein receptor related protein 6; and LRP5: Low-density lipoprotein receptor related protein 5.