Similarities and differences between mesenchymal stem/progenitor cells derived from various human tissues

Figure 2 Percentage of mesenchymal stem cells population positive for CD73, CD90, CD105, and CD146 in bone marrow - mesenchymal stem cells, adipose tissue - mesenchymal stem cells, and skin - mesenchymal stem cells, and CD56 only in skeletal muscle - mesenchymal stem cells. Mesenchymal stem cells (MSCs) isolated from all examined tissues maintained the naïve MSC phenotype CD73, CD90, and CD105 during the follow-up period. A higher level of CD146 was observed in P1 in BM-MSCs, AT-MSCs, and SM-MSCs, but declined in the subsequent passages. In contrast, SK-MSC P1 was characterized with a low number of CD146+ cells; their level increased in P9. CD56 positive cells were present only in SM-MSCs, and the highest level was observed in P5. BM-MSC: Bone marrow - mesenchymal stem cell; AT-MSC: Adipose tissue - mesenchymal stem cell; SK-MSC: Skin - mesenchymal stem cell; SM-MSC: Skeletal muscle - mesenchymal stem cell.