Long non-coding RNA: The functional regulator of mesenchymal stem cells

doi:10.4252/wjsc.v11.i3.167

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Mar 26, 2019 (publication date) through Apr 25, 2024

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World Journal of Stem Cells

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1948-0210

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World J Stem Cells. Mar 26, 2019; 11(3): 167-179
Published online Mar 26, 2019. doi: 10.4252/wjsc.v11.i3.167

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Figure 1 Long non-coding RNA in the tri-lineage differentiation of mesenchymal stem cells. Mesenchymal stem cells possess the capacity for osteogenic, chondrogenic and adipogenic differentiation, and many long non-coding RNAs play an important role in this process. MSCs: Mesenchymal stem cells; LncRNA: Long non-coding RNA; HOTAIR: HOX transcript antisense RNA; GAS5: Growth arrest specific 5; MEG3: Maternally expressed 3; BMNCR: Bone marrow stem cell–related LncRNA; GAS5: Growth arrest specific 5; ROCR: Regulator of chondrogenesis RNA; DANCR: Differentiation antagonizing non-protein coding RNA; ZBED3-AS1: Zinc finger BED-type containing 3 antisense RNA 1; HULC: LncRNA-highly upregulated in liver cancer; MALAT: Metastasis-associated lung adenocarcinoma transcript; BDNF-AS: Brain-derived neurotrophic factor antisense.

Citation: Xie ZY, Wang P, Wu YF, Shen HY. Long non-coding RNA: The functional regulator of mesenchymal stem cells. World J Stem Cells 2019; 11(3): 167-179
URL: https://www.wjgnet.com/1948-0210/full/v11/i3/167.htm
DOI: https://dx.doi.org/10.4252/wjsc.v11.i3.167