Unmodified autologous stem cells at point of care for chronic myocardial infarction

Figure 13 Improvement or deterioration of regional replacement fibrosis after delivery of UA-ADRCs or saline. The panel shows mean and standard error of the mean of the results of replacement fibrosis analysis (as explained in detail in the main text) of segments that are assigned to the territory of the left anterior descending artery in the human heart LAD segments; analysis is also shown for segments that are assigned to the territory of the right coronary artery and the left circumflex coronary artery in the human heart (non-LAD segments) of animals in group 1 [delivery of UA-ADRCs) (green boxes) and group 2 (delivery of saline as control) (red boxes). Data above the zero line indicate improvement, and data below the zero line deterioration. Results of Bonferroni's multiple comparison tests are indicated (^bP < 0.01). LAD: Left anterior descending; UA-ADRCs: Fresh, uncultured, unmodified, autologous adipose-derived regenerative cells.