Unmodified autologous stem cells at point of care for chronic myocardial infarction

Figure 9 Change in body weight after delivery of UA-ADRCs or saline. The left panel shows group-specific mean ± SE of the body weight of animals in group 1 (delivery of UA-ADRCs) (green bars) and group 2 (delivery of saline as control) (red bars) at baseline (T0), 4 wk after infarction (T1) and 6 wk later (T2). In both groups, the mean body weight significantly increased during the investigated period (group 1: +48% from T0 to T1 and +97% from T0 to T2; group 2: +42% from T0 to T1 and +81% from T0 to T2; P_Interaction = 0.076; P_Time < 0.001; P_Treatment = 0.009; P_{Subjects (matching)} = 0.007). Post hoc Bonferroni tests for pairwise comparisons demonstrated a significant difference in mean body weight between the groups at T2 (^bP < 0.01) but not at T0 or T1. 95% confidence intervals (Bonferroni) of the differences of group-specific mean data are displayed in the right panel. UA-ADRCs: Fresh, uncultured, unmodified, autologous adipose-derived regenerative cells.