Systematic Reviews
Copyright ©The Author(s) 2022.
World J Stem Cells. Dec 26, 2022; 14(12): 851-867
Published online Dec 26, 2022. doi: 10.4252/wjsc.v14.i12.851
Figure 1
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Figure 1 Types of ischemic stroke. A: Thrombotic stroke occurs when thrombus formed from atherosclerosis blocks the blood flow; B: Embolic stroke occurs when a blood clot dislodges from a distant site and then travels to and lodges in an artery in the brain; C: Lacunar stroke occurs when a blood clot obstructs the normal blood flow in one of the small arteries found deep within the brain.
Figure 2
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Figure 2 Progressive study selection performed according to the PRISMA flow diagram search strategy.
Figure 3
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Figure 3 Summary of the collective literature data for a total of 19 different major types of material applied on seven different major types of stem/progenitor cells to enhance their therapeutic potential for ischemic stroke treatment. AATS: Recombinant human albumin, L-ascorbic acid 2-phosphate, human apo-transferrin, sodium selenite medium; ASP: Spermine-modified amylose; cRGD-Exo: Cyclo (Arg-Gly-Asp-D-Tyr-Lys) peptide-exosome; CS-A: Chondroitin sulfate-A; fmSiO4@SPION: Fluorescent mesoporous silica-coated superparamagnetic iron 1 oxide nanoparticle; HAMC: Hyaluronan methylcellulose; iPSCs-NPCs: Induced pluripotent stem cells/neural progenitor cells; LbL-NSCs: Layer-by-layer assembly of neural stem cells; MNBs: Magnetic nanobubbles; MNV: Magnetic nanovesicle; MSCs/ECs: Mesenchymal stem cells/endothelial cells; PβAE: Poly (β-amino esters); PA-CLEVSRKNC: Palmitic acid-peptide; PEG: Polyethylene glycol; PEI: Polyethylenimine; PLA-PRM; Polylactic acid polymeric rough microfibers; PLGA-PEG: Polylactic coglycolic acid­polyethylene glycol; SAP: Self-assembling peptide; SiO4@SPION: Silica-coated superparamagnetic iron 1 oxide nanoparticle; SPION: Superparamagnetic iron 1 oxide nanoparticle.