Synergistic effects of nimesulide and 5-fluorouracil on tumor growth and apoptosis in the implanted hepatoma in mice

Table 2 Apoptotic indices of nimesulide and 5-FU in mouse hepatoma tissues after the treatment with determined by FCM. n = 3, ^-x ± s

	Control	Nimesulide (20 mg/kg)	5-FU (20 mg/kg)	Nimesulide (20 mg/kg) + 5-FU (10 mg/kg)
Apoptotic Index	4.3 ± 1.5	29.0 ± 2.6ac	49.0 ± 2.0ac	72.0 ± 2.5a

^aP < 0.01 vs control;

^cP < 0.01 vs nimesulide + 5-FU.