Difference of gene expression profiles between esophageal carcinoma and its pericancerous epithelium by gene chip

Table 3 Function classification for genes showing expression differences in esophageal carcinoma and pericancerous epithelium that were > 2 or < 0.5 fold from the control tissue

	Gene function classification	Carcinoma/normal			Pericancerous/normal
		N	> 2	< 0.5	N	> 2	< 0.5
1	Proto-oncogenes and tumor suppression genes	2	1	1	0	0	0
2	Cell signals and transducing proteins	3	2	1	3	3	0
3	Cell cycle proteins	6	5	1	0	0	0
4	Extra-pressure reaction proteins	1	0	1	0	0	0
5	Cell regulatory proteins	7	7	0	3	3	0
6	Cell apoptosis related proteins	1	1	0	1	0	1
7	DNA synthesis, repair and recombinant proteins	3	3	0	0	0	0
8	DNA binding, transcription and its factor	6	4	2	1	1	0
9	Cell receptors	0	0	0	0	0	0
10	Cell surface antigen and adhesion proteins	10	8	2	4	4	0
11	Ion-channel and transporters	24	14	10	2	2	0
12	Metabolism-related proteins	21	10	11	6	4	2
13	Protein synthesis-related genes	14	7	7	2	1	1
14	Development-related genes	1	1	0	2	2	0
15	Other genes	27	18	9	7	7	0
16	New genes	9	4	5	0	0	0
Total		135	85	50	31	27	4