Alterations of intestinal mucosa structure and barrier function following traumatic brain injury in rats

Table 2 Changes in villous height, diameter, crypt depth and surface area of mucosa

Groups	Villous height (µm)	Villous diameter (µm)	Crypt depth (µm)	Surface area (mm2)
Control	229.2 ± 18.1	37.4 ± 5.5	79.3 ± 9.6	0.0259 ± 0.0048
TBI 3 hours	219.5 ± 21.2	37.6 ± 6.1	78.9 ± 9.4	0.0258 ± 0.0035
TBI 12 hours	214.5 ± 22.5	35.6 ± 3.1	74.0 ± 6.9	0.0241 ± 0.0037
TBI 24 hours	189.2 ± 13.6b	32.7 ± 3.2	67.0 ± 7.6bc	0.0195 ± 0.0012bc
TBI 72 hours	150.8 ± 10.4bc	32.1 ± 4.2	34.8 ± 5.6bc	0.0151 ± 0.0010bc
TBI 7 days	136.7 ± 15.7bc	30.8 ± 5.8	38.3 ± 6.1bc	0.0130 ± 0.0015bc

Note: Values were expressed as mean ± SD.

^bP < 0.01 vs control,

^cP < 0.01 vs group of 3 hour TBI.