Diagnostic value of platelet derived growth factor-BB, transforming growth factor-&beta;1, matrix metalloproteinase-1, and tissue inhibitor of matrix metalloproteinase-1 in serum and peripheral blood mononuclear cells for hepatic fibrosis

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Nov 15, 2003 (publication date) through Apr 25, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Viral Hepatitis

World J Gastroenterol. Nov 15, 2003; 9(11): 2490-2496
Published online Nov 15, 2003. doi: 10.3748/wjg.v9.i11.2490

Table 7 Parameters of the combined diagnosis in the serial test

Combined indices	Sensitivity (%)	Specificity (%)
PDGF-BB + TIMP-1mRNA	66.3	100
PDGF-BB + TIMP-1mRNA/MMP-1mRNA	59.2	100
PDGF-BB + HA	56.0	99.4
TIMP-1mRNA + TIMP-1mRNA/MMP-1mRNA	48.5	100
TIMP-1mRNA + HA	45.7	100
PDGF-BB + TIMP-1mRNA + HA	41.1	100
TIMP-1mRNA/MMP-1mRNA + HA	40.8	100
TIMP-1mRNA + TIMP-1mRNA/MMP-1mRNA + PDGF-BB	40.4	100
PDGF-BB + TIMP-1mRNA/MMP-1mRNA + HA	36.7	100
TIMP-1mRNA + TIMP-1mRNA/MMP-1mRNA + HA	30.1	100
TIMP-1mRNA + TIMP-1mRNA/MMP-1mRNA + PDGF-BB + HA	27.1	100

Citation: Zhang BB, Cai WM, Weng HL, Hu ZR, Lu J, Zheng M, Liu RH. Diagnostic value of platelet derived growth factor-BB, transforming growth factor-β₁, matrix metalloproteinase-1, and tissue inhibitor of matrix metalloproteinase-1 in serum and peripheral blood mononuclear cells for hepatic fibrosis. World J Gastroenterol 2003; 9(11): 2490-2496
URL: https://www.wjgnet.com/1007-9327/full/v9/i11/2490.htm
DOI: https://dx.doi.org/10.3748/wjg.v9.i11.2490