Diagnostic value of platelet derived growth factor-BB, transforming growth factor-β1, matrix metalloproteinase-1, and tissue inhibitor of matrix metalloproteinase-1 in serum and peripheral blood mononuclear cells for hepatic fibrosis

Table 1 Comparison of the serum level of PDGF-BB, TGF-β₁, TIMP-1, MMP-1 and TIMP-1/MMP-1 between patients and healthy blood donors (¯x±s)

Group (n)	PDGF-BB (n g/L)	TGF-β1 ( μg/L)	TIMP-1 ( μg/L)	MMP-1 ( μg/L)	TIMP-1/ MMP-1
Patients	67.75 ± 30.08b	31.41 ± 23.22	258.87 ± 77.75a	6.05 ± 4.44	83.66 ± 100.36b
Controls	19.85 ± 10.28	26.28 ± 16.69	205.80 ± 35.66	7.98 ± 3.13	31.95 ± 20.03
t	11.435	0.912	2.646	-1.79	3.176
P	0.000	0.365	0.01	0.077	0.002

There was a statistically significant difference as compared with the control group

^aP < 0.05,

^bP < 0.01.