Oxymatrine therapy for chronic hepatitis B: A randomized double-blind and placebo-controlled multi-center trial

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Nov 15, 2003 (publication date) through Apr 25, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Viral Hepatitis

World J Gastroenterol. Nov 15, 2003; 9(11): 2480-2483
Published online Nov 15, 2003. doi: 10.3748/wjg.v9.i11.2480

Table 1 Negative conversion rates of serum HBsAg and comparison among capsule oxymatrine group, injection oxymatrine group and placebo group

Index	Group	Positive number	Number of negative conversion	Negative conversionrate (%)	Comparison among 3 groups
Index	Group	Positive number	Number of negative conversion	Negative conversionrate (%)	χ²	P value
HBsAg	Capsule	101	2	1.98
	Injection	30	1	3.33		0.269
	Placebo	67	0	0.00
HBV DNA	Capsule	101	39	38.61
	Injection	30	13	43.33	22.716	0.001
	Placebo	67	5	7.46
HBeAg	Capsule	94	30	31.91
	Injection	28	11	39.29	17.042	0.001
	Placebo	62	4	6.45

The comparison of negative conversion rates of serum HBsAg, HBV DNA and HBeAg was performed with χ² test, statistic was χ².

Citation: Lu LG, Zeng MD, Mao YM, Li JQ, Wan MB, Li CZ, Chen CW, Fu QC, Wang JY, She WM, Cai X, Ye J, Zhou XQ, Wang H, Wu SM, Tang MF, Zhu JS, Chen WX, Zhang HQ. Oxymatrine therapy for chronic hepatitis B: A randomized double-blind and placebo-controlled multi-center trial. World J Gastroenterol 2003; 9(11): 2480-2483
URL: https://www.wjgnet.com/1007-9327/full/v9/i11/2480.htm
DOI: https://dx.doi.org/10.3748/wjg.v9.i11.2480