Association between HLA class II gene and susceptibility or resistance to chronic hepatitis B

Table 2 Allele frequency of HLA-DQA1 in patients with chronic and acute hepatitis B and normal heathy individuals

HLA-DQA1 allele	Normal control (n = 106)		Chronic hepatitis B (n = 52)		Acute hepatitis B (n = 30)
	PN	AF	PN	AF	PN	AF
0101	17	8.02	9	8.65	4	6.67
0102	45	21.23	22	21.15	12	20.00
0103	9	4.25	5	4.81	2	3.33
0104	3	1.42	1	0.96	1	1.67
0201	7	3.30	3	2.88	1	1.67
0301*	57	26.89	15	14.42	18	30.00
0302	1	0.47	0	0.00	0	0.00
0401	2	0.49	1	0.96	1	1.67
0501**	29	13.68	27	25.96	10	16.67
0601	23	10.85	12	11.54	6	10.00
Blank	19	8.96	9	8.65	5	8.33

PN: Positive number, AF: Allele frequency. *χ² = 7.6781, Pc = 0.0388, RR = 3.70. **χ² = 9.2002, Pc = 0.0157, RR = 2.87.