Oxidative DNA damage in peripheral leukocytes and its association with expression and polymorphisms of hOGG1: A study of adolescents in a high risk region for hepatocellular carcinoma in China

doi:10.3748/wjg.v9.i10.2186

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Oct 15, 2003 (publication date) through May 19, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Liver Cancer

World J Gastroenterol. Oct 15, 2003; 9(10): 2186-2193
Published online Oct 15, 2003. doi: 10.3748/wjg.v9.i10.2186

Table 2 Partial Correlation between biomarkers, age and BMI

	8-oxoGP (%)	8-oxoGI (RFI)	hOGG₁P (%)	hOGG₁I (RFI)	Double staining percentage (%)
8-oxoGP (%)^a		0.6987 (0.000)^f	0.8333 (0.000)^f	0.5299 (0.000)^f	0.9553 (0.000)^f
8-oxoGI (RFI)^a			0.4843 (0.000)^f	0.5155 (0.000)^f	0.7075 (0.000)^f
hOGG₁P (%)^a				0.6727 (0.000)^f	0.8482 (0.000)^f
hOGG₁I (RFI)^a					0.6528 (0.000)^f
Age^b	0.1832 (0.102)	-0.0326 (0.773)	0.3332 (0.002)^f	0.2316 (0.037)^e	0.1655 (0.140)
BMI^b	-0.3339 (0.002)^f	-0.0983 (0.383)	-0.3111 (0.005)^f	-0.0415 (0.713)	-0.2285 (0.0040)^f
Age^c	0.2414 (0.031)^e	-0.0204 (0.858)	0.3954 (0.000)^f	0.2390 (0.033)^e	0.2015 (0.073)
BMI^d	-0.3663 (0.001)^f	-0.0950 (0.402)	-0.3779 (0.001)^f	-0.0735 (0.517)	-0.2552 (0.022)^e

A: Adjusted for (gender + age + BMI), B: Adjusted for gender; C:Adjusted for (gender + BMI), D: Adjusted for (gender + age), E: Cor-relation was significant at the 0.05 level, F: Correlation was significant at the 0.01 level, G: Data presented in cells were correlation coefficient (P).

Citation: Peng T, Shen HM, Liu ZM, Yan LN, Peng MH, Li LQ, Liang RX, Wei ZL, Halliwell B, Ong CN. Oxidative DNA damage in peripheral leukocytes and its association with expression and polymorphisms of hOGG₁: A study of adolescents in a high risk region for hepatocellular carcinoma in China. World J Gastroenterol 2003; 9(10): 2186-2193
URL: https://www.wjgnet.com/1007-9327/full/v9/i10/2186.htm
DOI: https://dx.doi.org/10.3748/wjg.v9.i10.2186