Esophageal Cancer
Copyright ©The Author(s) 2003.
World J Gastroenterol. Jan 15, 2003; 9(1): 9-15
Published online Jan 15, 2003. doi: 10.3748/wjg.v9.i1.9
Table 3 Genes up or down regulated in all five stages of grade II basal cell hyperplasia, high-grade dysplasia, carcinoma in situ, early and advanced squamous cell carcinoma. Position indicates the gene position on the microarray membrane
PositionGene Name
Up Regulated Genes
A2kG1/S-specific cyclin C
A4iERK5
A4jERK6
A5bERK activator kinase 1
A5ltranscription factor DP2
B3gcaspase-8 precursor
B3icaspase-9 precursor
B3jcaspase-10 precursor (CASP10)
C1aDNA-dependent protein kinase
C2cDNA-repair protein XRCC1
C2jRAD1
C4bWnt-5A
C4kDVL1
C6mCCK4
C7kretinoic acid receptor epsilon
C7lretinoic acid receptor gamma 1
C7mretinoic acid receptor beta
D4bintegrin alpha 8
D4jintegrin beta 7 precursor
D4kintegrin beta 8 precursor
D5gezrin; cytovillin 2; villin 2
D5jCD56 antigen
D7fplacenta growth factor 1
E1fMMP9
E2aMMP18
F3jearly growth response protein 1
F4lIL-6
F5eIL-13
F5kinterferon gamma precursor
F5lleukocyte interferon-inducible peptide
Down regulated Genes
C6cinsulin-like growth factor binding protein 2 (IGFBP2P2)
F4dinterleukin-1 receptor antagonist protein precursor (IL-1RA; IRAP)