Transplantation of human hepatocytes into tolerized genetically immunocompetent rats

Figure 4 Confocal immunofluorescence microscopy for detection of human albumin in rat livers at wk16 post-transplantation. Panel A, a representative rat intrafetally injected with primary hepatocytes and subsequently transplanted with those same cells, stained with monoclonal goat anti-rat albumin. Panel B, a section from the same sample stained with monoclonal mouse anti-human albumin antibody. Panel C, a representative rat intrafetally injected with primary human hepatocytes, but not transplanted with hepatocytes, stained with anti-human albumin antibody. Panel D, the same sample as in Panel A stained with only second antibody. Magnification, × 250.