Effect of Boschniakia rossica on expression of GST-P, p53 and p21ras proteins in early stage of chemical hepatocarcinogenesis and its anti-inflammatory activities in rats

Table 2 Effect of BR-extract on xylene-induced mouse ear edema

Groups	Dose (mg/kg)	Mouse (n)		BR-H2O fraction (I)		BR-CH2Cl2 fraction (II)
		I	II	Edema degree (mg)	Inhibitory rate (%)	Edema degree (mg)	Inhibitory rate (%)
NS (A)	0.85%	10	20	19.1 ± 3.6*		11.2 ± 4.0
Ind (B)	20	10	20	15.5 ± 1.8a	18.8	8.8 ± 2.6a	21.5
BR (C)	500	10	20	17.4 ± 3.1b	8.9	8.3 ± 3.9a	26.2
BR (D)	1000	10	20	13.6 ± 3.1a	28.8	8.1 ± 3.7a	27.4

^*¯x ± s,

^aP < 0.05;

^bP < 0.01, vs NS (t test); NS: normal saline; Ind: indomethacin; BR: Boschniakia rossica