Co-morbidity, not age predicts adverse outcome in Clostridium difficile colitis

Table 2 Co-morbidity vs adverse outcome at discharge

Variable	Not predictive	Predictive	P value
Co-morbidity
Cardiac disease (1)	—	×	0.036
COPD	×	—	0.200
Dementia	×	—	0.075
Diabetes	×	—	0.622
Hypertension	×	—	0.387
Elevated BUN	—	×	0.039
High creatinine	×	—	0.106
Low creatinine clearance	×	—	0.928
Nutrition related
Tube-fed	×	—	0.241
Low serum total protein	—	×	0.034
Low serum albumin	—	×	0.001
Sepsis related
Aminoglycosides	×	—	0.034
Clindamycin	—	×	0.004
Penicillin-like (2)	—	×	0.035
Antibiotic use ＞ 4 wk	—	×	0.010
Use of ＞ 4 antibiotics	—	×	0.026
Fever (＞ 38.3 °C)	×	—	0.181
Infection ＞ 4 wk	—	×	0.007

Results are given as predictive or not predictive of death as the adverse outcome and were determined using logistic regression analysis. (1): 64 cardiac patients were identified with 19 deaths during hospitalization. (2): Excluding cephalosporins.