Clinicopathologic and biomolecular features of interval colorectal cancers in Korean patients: A KASID multicenter prospective study

Table 2 Comparison of biomolecular features between interval and sporadic colorectal cancers, before and after propensity score weighting, n (%)

		Before PSW				After PSW
		Interval CRC (n = 28)	Sporadic CRC (n = 79)	P value	SMD	Interval CRC (n = 23.60)	Sporadic CRC (n = 67.48)	P value	SMD
CIMP	Negative	23 (82.1)	75 (94.9)	0.036	0.410	26.5 (93.8)	76.0 (95.5)	0.670	0.077
	Positive	5 (17.9)	4 (5.1)			1.5 (6.2)	3.0 (4.5)
KRAS	Wild type	23 (82.1)	50 (63.3)	0.066	0.433	22.0 (74.6)	55.9 (65.8)	0.641	0.194
	Non-wild type	5 (17.9)	29 (36.7)			6.0 (25.4)	23.1 (34.2)
MSI	MSS	27 (96.4)	76 (96.2)	0.957	0.012	27.2 (96.7)	76.7 (96.6)	0.981	0.005
	MSI	1 (3.6)	3 (3.8)			0.8 (3.3)	2.3 (3.4)
BRAF	Negative	25 (89.3)	76 (96.2)	0.172	0.269	27.1 (96.0)	76.7 (96.6)	0.846	0.034
	Positive	3 (10.7)	3 (3.8)			0.9 (4.0)	2.3 (3.4)

PSW: Propensity score weighting; CRC: Colorectal cancer; SMD: Standardized mean difference; CIMP: CpG island methylator phenotype; MSI: Microsatellite instability; MSS: Microsatellite-stable.