Serum pepsinogen combined with computed tomography imaging for diagnosing recurrence of gastric cancer after total gastrectomy

doi:10.3748/wjg.124537

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Jan 14, 2027; 33(2): 124537
Published online Jan 14, 2027. doi: 10.3748/wjg.124537

Table 3 Diagnostic performance of serum pepsinogen, computed tomography imaging, and the combined model for recurrence after total gastrectomy

Variables	AUC	95%CI	Sensitivity	Specificity	P value
Serum PG	0.94	0.88-0.98	0.92	0.96	< 0.0001^b
CT imaging	0.78	0.69-0.86	0.63	0.93	< 0.0001^b
Combined model	0.98	0.93-1.00	1.00	0.91	< 0.0001^b

^bP < 0.01.

P values indicate whether each area under the curve is significantly different from 0.5. AUC: Area under the curve; CI: Confidence interval; CT: Computed tomography; PG: Pepsinogen.

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Citation: Zhang JR, Xu XW, Liu JM, Zhu ZH, Mao CM. Serum pepsinogen combined with computed tomography imaging for diagnosing recurrence of gastric cancer after total gastrectomy. World J Gastroenterol 2027; 33(2): 124537
URL: https://www.wjgnet.com/1007-9327/full/v33/i2/124537.htm
DOI: https://dx.doi.org/10.3748/wjg.124537

Zhang JR, Xu XW, Liu JM, Zhu ZH, Mao CM. Serum pepsinogen combined with computed tomography imaging for diagnosing recurrence of gastric cancer after total gastrectomy. World J Gastroenterol 2027; 33(2): 124537 [DOI: 10.3748/wjg.124537]

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