Serum pepsinogen combined with computed tomography imaging for diagnosing recurrence of gastric cancer after total gastrectomy

doi:10.3748/wjg.124537

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Jan 14, 2027; 33(2): 124537
Published online Jan 14, 2027. doi: 10.3748/wjg.124537

Table 2 Comparison of positive rates for serum pepsinogen and computed tomography imaging in diagnosing postoperative recurrence, n (%)

Group	n	Serum PG⁺	CT imaging⁺	McNemar χ²	df	P value
Total	110	62 (56.36)	44 (40.00)	9.03	1	0.0027^b
Recurrence	65	60 (92.31)	41 (63.08)	11.17	1	0.0008^b

^bP < 0.01.

Serum pepsinogen (PG)+ was defined as PG I > 26.93 ng/mL and/or PG II > 0.96 ng/mL. Computed tomography (CT) imaging+ indicates definitive signs of recurrence or metastasis. The McNemar test with continuity correction was used to compare paired positivity rates between serum PG and CT imaging. CT: Computed tomography; PG: Pepsinogen.

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Citation: Zhang JR, Xu XW, Liu JM, Zhu ZH, Mao CM. Serum pepsinogen combined with computed tomography imaging for diagnosing recurrence of gastric cancer after total gastrectomy. World J Gastroenterol 2027; 33(2): 124537
URL: https://www.wjgnet.com/1007-9327/full/v33/i2/124537.htm
DOI: https://dx.doi.org/10.3748/wjg.124537

Zhang JR, Xu XW, Liu JM, Zhu ZH, Mao CM. Serum pepsinogen combined with computed tomography imaging for diagnosing recurrence of gastric cancer after total gastrectomy. World J Gastroenterol 2027; 33(2): 124537 [DOI: 10.3748/wjg.124537]

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