Serum pepsinogen combined with computed tomography imaging for diagnosing recurrence of gastric cancer after total gastrectomy

Table 1 Baseline characteristics of the study population, n (%)

Variables	Total (n = 110)	Recurrence (n = 65)	No recurrence (n = 45)	P value
Age (years), mean ± SD	66.13 ± 8.83	67.11 ± 8.64	64.71 ± 9.01	0.1626
Age range (years)	34-88	34-88	37-81	-
Sex				0.3295
Male	84 (76.36)	47 (72.31)	37 (82.22)
Female	26 (23.64)	18 (27.69)	8 (17.78)
Tumor location				0.2434
Cardia	70 (63.64)	46 (70.77)	24 (53.33)
Gastric body	30 (27.27)	15 (23.08)	15 (33.33)
Gastric antrum	8 (7.27)	4 (6.15)	4 (8.89)
Gastric angle	1 (0.91)	0 (0.00)	1 (2.22)
Pylorus	1 (0.91)	0 (0.00)	1 (2.22)
Pathological stage				0.0004b
I	18 (16.36)	6 (9.23)	12 (26.67)
II	19 (17.27)	8 (12.31)	11 (24.44)
III	58 (52.73)	38 (58.46)	20 (44.44)
IV	15 (13.64)	13 (20.00)	2 (4.44)
Histological subtype				0.1825
Differentiated	48 (43.64)	32 (49.23)	16 (35.56)
Undifferentiated	56 (50.91)	28 (43.08)	28 (62.22)
Mucinous adenocarcinoma	4 (3.64)	3 (4.62)	1 (2.22)
Signet ring cell carcinoma	2 (1.82)	2 (3.08)	0 (0.00)

^bP < 0.01.

Percentages may not total 100% due to rounding. All patients underwent R0 radical total gastrectomy and received neoadjuvant therapy. Continuous variables were compared using independent-samples t test; categorical variables were compared using χ² test or Fisher’s exact test as appropriate.