Total bile acid better reflects the early biochemical biliary drainage response after endoscopic retrograde cholangiopancreatography

Figure 2 Early postoperative changes in total bile acid, direct bilirubin, and total bilirubin after therapeutic biliary endoscopic retrograde cholangiopancreatography. A: Median trajectories of total bile acid, direct bilirubin, and total bilirubin at baseline, within 24 hours after endoscopic retrograde cholangiopancreatography (ERCP), and within 5 days after endoscopic retrograde cholangiopancreatography; B: Relative decline from baseline at 24 hours after ERCP; C: Relative decline from baseline within 5 d after ERCP; D: Cross-marker comparison using the decline index [-log (postoperative/baseline ratio)]. Higher values indicate greater postoperative decline from baseline. Box plots show medians and interquartile ranges. ^dP < 0.0001; IQR: Interquartile range; TBA: Total bile acid; Dbil: Direct bilirubin; Tbil: Total bilirubin.