Total bile acid better reflects the early biochemical biliary drainage response after endoscopic retrograde cholangiopancreatography

doi:10.3748/wjg.123951

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World Journal of Gastroenterology

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1007-9327

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Retrospective Cohort Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Jan 14, 2027; 33(2): 123951
Published online Jan 14, 2027. doi: 10.3748/wjg.123951

Table 5 Cross-marker comparisons of total bile acid, direct bilirubin, and total bilirubin after endoscopic retrograde cholangiopancreatography (paired comparisons)

Time point	Comparison	n	Median decline of first marker (%)	Median decline of second marker (%)	P value	Adjusted P value
24 hours after ERCP	TBA vs Dbil	836	79.69	5.70	< 0.001	< 0.001
24 hours after ERCP	TBA vs Tbil	836	79.69	3.98	< 0.001	< 0.001
5 days after ERCP	TBA vs Dbil	836	92.00	18.58	< 0.001	< 0.001
5 days after ERCP	TBA vs Tbil	836	92.00	17.91	< 0.001	< 0.001

Table 5 presents paired within-patient comparisons of relative decline between markers. Higher relative decline indicates greater postoperative reduction from baseline. ERCP: Endoscopic retrograde cholangiopancreatography; TBA: Total bile acid; Dbil: Direct bilirubin; Tbil: Total bilirubin.

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Citation: Liao GL, Wei HX, Qin JF, Qin F, Wang J, Liu SQ, Huang JA, Qin MB. Total bile acid better reflects the early biochemical biliary drainage response after endoscopic retrograde cholangiopancreatography. World J Gastroenterol 2027; 33(2): 123951
URL: https://www.wjgnet.com/1007-9327/full/v33/i2/123951.htm
DOI: https://dx.doi.org/10.3748/wjg.123951

Liao GL, Wei HX, Qin JF, Qin F, Wang J, Liu SQ, Huang JA, Qin MB. Total bile acid better reflects the early biochemical biliary drainage response after endoscopic retrograde cholangiopancreatography. World J Gastroenterol 2027; 33(2): 123951 [DOI: 10.3748/wjg.123951]

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