Novel intermittent electrocoagulation technique reduces post-endoscopic submucosal dissection electrocoagulation syndrome in colorectal neoplasms

Table 3 Univariate and multivariate analysis of risk factors of post-endoscopic submucosal dissection electrocoagulation syndrome

Factors	Univariate analysis		Multivariate analysis
	OR (95%CI)	P value	OR (95%CI)	P value
Electrocoagulation method		0.037		0.041
C-ESD	1.00 (reference)		1.00 (reference)
I-ESD	0.40 (0.17-0.95)		0.38 (0.15-0.96)
Sex		0.043		0.028
Male	1.00 (reference)		1.00 (reference)
Female	2.36 (1.03-5.41)		2.72 (1.12-6.61)
Age, years		0.543
≤ 60	1.00 (reference)
> 60	0.78 (0.35-1.74)
ASA		0.467
1	1.00 (reference)
2	1.35 (0.60-3.02)
History of malignancy		0.976
No	1.00 (reference)
Yes	1.02 (0.28-3.72)
Location
Right side of colon	1.00 (reference)
Left side of colon	1.45 (0.53-3.95)	0.471
Rectum	0.65 (0.25-1.72)	0.387
Size, mm		0.016		0.019
< 20	1.00 (reference)		1.00 (reference)
≥ 20	3.04 (1.23-7.51)		3.43 (1.22-9.61)
Procedural time, minute		0.040		0.242
≤ 60	1.00 (reference)		1.00 (reference)
> 60	2.38 (1.04-5.44)		1.72 (0.69-4.24)
LST classification		0.964
LST-G	1.00 (reference)
LST-NG	1.03 (0.30-3.49)
Histopathology		0.801
Serrated lesion	1.00 (reference)
Adenoma	0.89 (0.35-2.25)
Muscle layer exposure		0.009		0.008
No	1.00 (reference)		1.00 (reference)
Yes	5.09 (1.49-17.39)		7.10 (1.65-30.57)

OR: Odds ratio; CI: Confidence interval; I-ESD: Intermittent electrocoagulation; C-ESD: Conventional continuous electrocoagulation; ASA: American Society of Anesthesiologists physical status classification; LST: Laterally spreading tumor.