Prognostic impact of neoadjuvant therapy vs upfront surgery in patients with huge hepatocellular carcinoma undergoing curative resection

doi:10.3748/wjg.122833

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World Journal of Gastroenterology

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1007-9327

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Jan 14, 2027; 33(2): 122833
Published online Jan 14, 2027. doi: 10.3748/wjg.122833

Table 2 Intraoperative bleeding and postoperative hospital stay of patients, median (interquartile range)

Variable	Upfront surgery (n = 47)	Neoadjuvant therapy (n = 56)	P value
Blood loss (mL)	521.00 (200.00, 600.00)	421.00 (100.00, 600.00)	0.894
Operation time (minute)	258.00 (198.00, 311.00)	258.00 (191.50, 300.00)	0.625
Postoperative hospitalization time (day)	12.00 (7.00, 15.00)	9.00 (6.00, 11.00)	0.052
Intraoperative blood transfusion, n (%)	17 (36.2)	23 (41.1)	0.611

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Citation: Lang MR, Han RY, Zhu FY, Wang ZH, Zhai JX, Luo M, Hu YW, Tao CC, Siqin TN, Sun J, Lu ZY, Zhao JJ, Tong JX, Wang X, Cao DY, Wang LM, Rong WQ, Wu JX, Meng X, Wang HG. Prognostic impact of neoadjuvant therapy vs upfront surgery in patients with huge hepatocellular carcinoma undergoing curative resection. World J Gastroenterol 2027; 33(2): 122833
URL: https://www.wjgnet.com/1007-9327/full/v33/i2/122833.htm
DOI: https://dx.doi.org/10.3748/wjg.122833

Lang MR, Han RY, Zhu FY, Wang ZH, Zhai JX, Luo M, Hu YW, Tao CC, Siqin TN, Sun J, Lu ZY, Zhao JJ, Tong JX, Wang X, Cao DY, Wang LM, Rong WQ, Wu JX, Meng X, Wang HG. Prognostic impact of neoadjuvant therapy vs upfront surgery in patients with huge hepatocellular carcinoma undergoing curative resection. World J Gastroenterol 2027; 33(2): 122833 [DOI: 10.3748/wjg.122833]

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